Ki Summary

Reaction Details

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Target

Beta-lactamase

Ligand

BDBM51991

Substrate/Competitor

n/a

Meas. Tech.

FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts.

IC50

1161±n/a nM

Citation

PubChem, PC FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts. PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Beta-lactamase

Name:

Beta-lactamase

Synonyms:

Beta lactamase

Type:

Enzyme Catalytic Domain

Mol. Mass.:

31513.38

Organism:

Pseudomonas aeruginosa

Description:

gi_114881106

Residue:

286

Sequence:

MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW

BDBM51991

n/a

Name

BDBM51991

Synonyms:

3-[[(E)-[2-(3-bromobenzyl)oxybenzylidene]amino]thiocarbamoylamino]benzoic acid | 3-[[[2-(3-bromobenzyl)oxybenzylidene]amino]thiocarbamoylamino]benzoic acid | 3-[[[2-[(3-bromophenyl)methoxy]phenyl]methylideneamino]carbamothioylamino]benzoic acid | 3-[[[2-[[2-[(3-bromophenyl)methoxy]phenyl]methylidene]hydrazinyl]-sulfanylidenemethyl]amino]benzoic acid | 3-{[(2-{2-[(3-bromobenzyl)oxy]benzylidene}hydrazino)carbonothioyl]amino}benzoic acid | MLS000681697 | SMR000312741 | cid_16195447

Type

Small organic molecule

Emp. Form.

C22H18BrN3O3S

Mol. Mass.

484.366

SMILES

OC(=O)c1cccc(NC(=S)NN=Cc2ccccc2OCc2cccc(Br)c2)c1 |w:12.11|

Structure