| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM52040 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts. |
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| IC50 | 1606±n/a nM |
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| Citation |  PubChem, PC FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts. PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | Beta lactamase |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 31513.38 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | gi_114881106 |
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| Residue: | 286 |
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| Sequence: | MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
|
|
|
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| BDBM52040 |
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| n/a |
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| Name | BDBM52040 |
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| Synonyms: | MLS001075359 | SMR000646445 | [3-(4-chlorophenyl)-5-(2-furyl)-2-pyrazolin-1-yl]-(2-furyl)methanone | [5-(4-chlorophenyl)-3-(2-furanyl)-3,4-dihydropyrazol-2-yl]-(2-furanyl)methanone | [5-(4-chlorophenyl)-3-(furan-2-yl)-3,4-dihydropyrazol-2-yl]-(furan-2-yl)methanone | cid_3248551 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H13ClN2O3 |
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| Mol. Mass. | 340.76 |
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| SMILES | Clc1ccc(cc1)C1=NN(C(C1)c1ccco1)C(=O)c1ccco1 |t:8| |
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| Structure | 
|
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