| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 6 |
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| Ligand | BDBM34176 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | MKP-3 in vitro HTS assay |
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| IC50 | 10000±n/a nM |
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| Citation |  PubChem, PC MKP-3 in vitro HTS assay PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Dual specificity protein phosphatase 6 |
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| Name: | Dual specificity protein phosphatase 6 |
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| Synonyms: | DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42303.19 |
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| Organism: | Rattus norvegicus |
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| Description: | gi_16758752 |
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| Residue: | 381 |
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| Sequence: | MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPG
IMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLK
KLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDI
ESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT
PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS
VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQ
QLYFTAPSNQNVYQVDSLQST
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| BDBM34176 |
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| n/a |
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| Name | BDBM34176 |
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| Synonyms: | (3E)-6-methoxy-3-(5-phenyl-1,2,4-oxadiazol-3-ylidene)-2-quinolinone | (3E)-6-methoxy-3-(5-phenyl-1,2,4-oxadiazol-3-ylidene)carbostyril | (3E)-6-methoxy-3-(5-phenyl-1,2,4-oxadiazol-3-ylidene)quinolin-2-one | MLS000082766 | SMR000045571 | cid_5389865 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H13N3O3 |
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| Mol. Mass. | 319.3141 |
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| SMILES | COc1ccc2[nH]c(=O)c(cc2c1)-c1noc(n1)-c1ccccc1 |
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| Structure | 
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