| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 6 |
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| Ligand | BDBM33065 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | MKP-3 in vitro HTS assay |
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| IC50 | 10000±n/a nM |
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| Citation |  PubChem, PC MKP-3 in vitro HTS assay PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Dual specificity protein phosphatase 6 |
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| Name: | Dual specificity protein phosphatase 6 |
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| Synonyms: | DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42303.19 |
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| Organism: | Rattus norvegicus |
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| Description: | gi_16758752 |
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| Residue: | 381 |
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| Sequence: | MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPG
IMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLK
KLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDI
ESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT
PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS
VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQ
QLYFTAPSNQNVYQVDSLQST
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| BDBM33065 |
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| n/a |
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| Name | BDBM33065 |
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| Synonyms: | 1-[[2,3-bis(2-furyl)quinoxalin-6-yl]carbamoyl]isonipecotic acid ethyl ester | 1-[[[2,3-bis(2-furanyl)-6-quinoxalinyl]amino]-oxomethyl]-4-piperidinecarboxylic acid ethyl ester | MLS000113285 | SMR000109188 | cid_2925160 | ethyl 1-[[2,3-bis(furan-2-yl)quinoxalin-6-yl]carbamoyl]piperidine-4-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C25H24N4O5 |
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| Mol. Mass. | 460.4819 |
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| SMILES | CCOC(=O)C1CCN(CC1)C(=O)Nc1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1 |
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| Structure | 
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