| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 6 |
|---|
| Ligand | BDBM51767 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | MKP-3 in vitro HTS assay |
|---|
| IC50 | 24300±n/a nM |
|---|
| Citation |  PubChem, PC MKP-3 in vitro HTS assay PubChem Bioassay(2009)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Dual specificity protein phosphatase 6 |
|---|
| Name: | Dual specificity protein phosphatase 6 |
|---|
| Synonyms: | DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 42303.19 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | gi_16758752 |
|---|
| Residue: | 381 |
|---|
| Sequence: | MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPG
IMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLK
KLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDI
ESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT
PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS
VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQ
QLYFTAPSNQNVYQVDSLQST
|
|
|
|---|
| BDBM51767 |
|---|
| n/a |
|---|
| Name | BDBM51767 |
|---|
| Synonyms: | 2-[(4-methyl-2-quinolyl)thio]-N-[5-(p-tolyl)-1,2,4-thiadiazol-3-yl]acetamide | MLS000586735 | N-[5-(4-methylphenyl)-1,2,4-thiadiazol-3-yl]-2-(4-methylquinolin-2-yl)sulfanyl-ethanamide | N-[5-(4-methylphenyl)-1,2,4-thiadiazol-3-yl]-2-(4-methylquinolin-2-yl)sulfanylacetamide | N-[5-(4-methylphenyl)-1,2,4-thiadiazol-3-yl]-2-[(4-methyl-2-quinolinyl)thio]acetamide | N-[5-(4-methylphenyl)-1,2,4-thiadiazol-3-yl]-2-[(4-methylquinolin-2-yl)thio]acetamide | SMR000208666 | cid_4256434 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H18N4OS2 |
|---|
| Mol. Mass. | 406.524 |
|---|
| SMILES | Cc1ccc(cc1)-c1nc(NC(=O)CSc2cc(C)c3ccccc3n2)ns1 |
|---|
| Structure | 
|
|---|
Search and Browse
