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TargetMKP-3
LigandBDBM46224
Substrate/Competitorn/a
Meas. Tech.MKP-3 in vitro HTS assay
IC50 84500±n/a nM
Citation PubChem PC MKP-3 in vitro HTS assay PubChem Bioassay (2009)[AID]  Article
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
MKP-3
Name:MKP-3
Synonyms:MAP kinase phosphatase 3 | Mitogen-activated protein kinase phosphatase 3
Type:Enzyme
Mol. Mass.:42303.19
Organism:Rattus norvegicus
Description:gi_16758752
Residue:381
Sequence:
MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPG
IMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLK
KLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDI
ESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT
PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS
VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQ
QLYFTAPSNQNVYQVDSLQST
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  Blast E-value cutoff:
BDBM46224
n/a
NameBDBM46224
Synonyms:2-[2-bromanyl-4-[(Z)-[2-[(4-ethylphenyl)amino]-4-oxidanylidene-1,3-thiazol-5-ylidene]methyl]-6-methoxy-phenoxy]ethanoic acid | 2-[2-bromo-4-[(Z)-[2-(4-ethylanilino)-4-keto-2-thiazolin-5-ylidene]methyl]-6-methoxy-phenoxy]acetic acid | 2-[2-bromo-4-[(Z)-[2-(4-ethylanilino)-4-oxo-1,3-thiazol-5-ylidene]methyl]-6-methoxyphenoxy]acetic acid | 2-[2-bromo-4-[(Z)-[2-(4-ethylanilino)-4-oxo-5-thiazolylidene]methyl]-6-methoxyphenoxy]acetic acid | MLS-0343544.0001 | cid_5765581
TypeSmall organic molecule
Emp. Form.C21H19BrN2O5S
Mol. Mass.491.355
SMILESCCc1ccc(NC2=NC(=O)C(S2)=Cc2cc(Br)c(OCC(O)=O)c(OC)c2)cc1 |w:13.14,t:7|
Structure
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