| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 6 |
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| Ligand | BDBM51781 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | MKP-3 in vitro HTS assay |
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| IC50 | 1360±n/a nM |
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| Citation |  PubChem, PC MKP-3 in vitro HTS assay PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Dual specificity protein phosphatase 6 |
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| Name: | Dual specificity protein phosphatase 6 |
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| Synonyms: | DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42303.19 |
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| Organism: | Rattus norvegicus |
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| Description: | gi_16758752 |
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| Residue: | 381 |
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| Sequence: | MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPG
IMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLK
KLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDI
ESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT
PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS
VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQ
QLYFTAPSNQNVYQVDSLQST
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| BDBM51781 |
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| n/a |
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| Name | BDBM51781 |
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| Synonyms: | (5E)-1-(4-fluorophenyl)-5-(2-furanylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione | (5E)-1-(4-fluorophenyl)-5-(2-furfurylidene)-2-thioxo-hexahydropyrimidine-4,6-quinone | (5E)-1-(4-fluorophenyl)-5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione | 1-(4-Fluoro-phenyl)-5-furan-2-ylmethylene-2-thioxo-dihydro-pyrimidine-4,6-dione | MLS001211808 | SMR000516340 | cid_777365 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H9FN2O3S |
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| Mol. Mass. | 316.307 |
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| SMILES | Fc1ccc(cc1)N1C(=S)NC(=O)C(=Cc2ccco2)C1=O |w:14.15| |
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| Structure | 
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