| Reaction Details |
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 | Report a problem with these data |
| Target | Integrin alpha-4 |
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| Ligand | BDBM39871 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose-Response of Allosteric Antagonists for the VLA-4 Integrin |
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| EC50 | 6500±n/a nM |
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| Citation |  PubChem, PC Dose-Response of Allosteric Antagonists for the VLA-4 Integrin PubChem Bioassay(2007)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Integrin alpha-4 |
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| Name: | Integrin alpha-4 |
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| Synonyms: | CD49 antigen-like family member D | CD49D | CD49d antigen | CD_antigen=CD49d | ITA4_HUMAN | ITGA4 | Integrin alpha-4 | Integrin alpha-4/beta-7 | Integrin alpha-IV | Integrin alpha4 | VLA-4 | VLA-4 subunit alpha | integrin alpha 4 precursor | integrin alpha-4 precursor |
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| Type: | Membrane Protein |
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| Mol. Mass.: | 114897.35 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P13612 |
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| Residue: | 1032 |
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| Sequence: | MAWEARREPGPRRAAVRETVMLLLCLGVPTGRPYNVDTESALLYQGPHNTLFGYSVVLHS
HGANRWLLVGAPTANWLANASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCGKTCLE
ERDNQWLGVTLSRQPGENGSIVTCGHRWKNIFYIKNENKLPTGGCYGVPPDLRTELSKRI
APCYQDYVKKFGENFASCQAGISSFYTKDLIVMGAPGSSYWTGSLFVYNITTNKYKAFLD
KQNQVKFGSYLGYSVGAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKELNILHEMKGK
KLGSYFGASVCAVDLNADGFSDLLVGAPMQSTIREEGRVFVYINSGSGAVMNAMETNLVG
SDKYAARFGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGISSTFSQRIEG
LQISKSLSMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLSHPESVN
RTKFDCVENGWPSVCIDLTLCFSYKGKEVPGYIVLFYNMSLDVNRKAESPPRFYFSSNGT
SDVITGSIQVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQ
PILQQKKEKDIMKKTINFARFCAHENCSADLQVSAKIGFLKPHENKTYLAVGSMKTLMLN
VSLFNAGDDAYETTLHVKLPVGLYFIKILELEEKQINCEVTDNSGVVQLDCSIGYIYVDH
LSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVHG
FVNPTSFVYGSNDENEPETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSFSPQTDKLF
NILDVQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKRLLYCIKADPHCLNF
LCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATGFPEPNPRVIELNKDENVA
HVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQEENRRD
SWSYINSKSNDD
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| BDBM39871 |
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| n/a |
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| Name | BDBM39871 |
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| Synonyms: | 3-butyl-2-keto-5-(morpholinomethyl)tetrahydrofuran-3-carboxylic acid ethyl ester | 3-butyl-5-(4-morpholinylmethyl)-2-oxo-3-oxolanecarboxylic acid ethyl ester | MLS000037648 | SMR000034771 | cid_661019 | ethyl 3-butyl-5-(morpholin-4-ylmethyl)-2-oxidanylidene-oxolane-3-carboxylate | ethyl 3-butyl-5-(morpholin-4-ylmethyl)-2-oxooxolane-3-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C16H27NO5 |
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| Mol. Mass. | 313.3893 |
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| SMILES | CCCCC1(CC(CN2CCOCC2)OC1=O)C(=O)OCC |
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| Structure | 
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