| Reaction Details |
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 | Report a problem with these data |
| Target | SUMO-conjugating enzyme UBC9 |
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| Ligand | BDBM61243 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation |
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| IC50 | 3610±n/a nM |
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| Citation |  PubChem, PC AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| SUMO-conjugating enzyme UBC9 |
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| Name: | SUMO-conjugating enzyme UBC9 |
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| Synonyms: | UBC9 | UBC9_HUMAN | UBCE9 | UBE2I | ubiquitin-conjugating enzyme E2I |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 18011.66 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_4507785 |
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| Residue: | 158 |
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| Sequence: | MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKL
RMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELL
NEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS
|
|
|
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| BDBM61243 |
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| n/a |
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| Name | BDBM61243 |
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| Synonyms: | 3-[[(E)-3-[4-(4-chlorobenzyl)oxy-3-methoxy-phenyl]-2-cyano-acryloyl]amino]benzoic acid | 3-[[(E)-3-[4-[(4-chlorophenyl)methoxy]-3-methoxy-phenyl]-2-cyano-prop-2-enoyl]amino]benzoic acid | 3-[[(E)-3-[4-[(4-chlorophenyl)methoxy]-3-methoxyphenyl]-2-cyano-1-oxoprop-2-enyl]amino]benzoic acid | 3-[[(E)-3-[4-[(4-chlorophenyl)methoxy]-3-methoxyphenyl]-2-cyanoprop-2-enoyl]amino]benzoic acid | MLS001172702 | SMR000591281 | cid_1516221 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H19ClN2O5 |
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| Mol. Mass. | 462.882 |
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| SMILES | COc1cc(\C=C(/C#N)C(=O)Nc2cccc(c2)C(O)=O)ccc1OCc1ccc(Cl)cc1 |
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| Structure | 
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