Reaction Details |
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Target | Cell division control protein 42 homolog |
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Ligand | BDBM54605 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype protein |
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Ki | 50±n/a nM |
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Citation | PubChem, PC Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype protein PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Cell division control protein 42 homolog |
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Name: | Cell division control protein 42 homolog |
Synonyms: | CDC42 | CDC42_HUMAN | Cell division control protein 42 homolog | G25K GTP-binding protein | cell division cycle 42 (GTP binding protein, 25kDa) |
Type: | PROTEIN |
Mol. Mass.: | 21258.36 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_652970 |
Residue: | 191 |
Sequence: | MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG
QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR
DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP
EPKKSRRCVLL
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BDBM54605 |
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n/a |
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Name | BDBM54605 |
Synonyms: | 1-[4-(difluoromethylsulfonyl)phenyl]-3,5-diphenyl-2-pyrazoline | 2-[4-(difluoromethylsulfonyl)phenyl]-3,5-diphenyl-3,4-dihydropyrazole | 2-[4-[bis(fluoranyl)methylsulfonyl]phenyl]-3,5-diphenyl-3,4-dihydropyrazole | UNM-0000305843 | cid_2857552 |
Type | Small organic molecule |
Emp. Form. | C22H18F2N2O2S |
Mol. Mass. | 412.452 |
SMILES | FC(F)S(=O)(=O)c1ccc(cc1)N1N=C(CC1c1ccccc1)c1ccccc1 |c:14| |
Structure |
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