BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetGTPase KRas [1-37]
LigandBDBM50022271
Substrate/Competitorn/a
Meas. Tech.Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype
EC50 30000±n/a nM
Citation PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype PubChem Bioassay(2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
GTPase KRas [1-37]
Name:GTPase KRas [1-37]
Synonyms:ras protein
Type:Enzyme Catalytic Domain
Mol. Mass.:4034.04
Organism:Homo sapiens (Human)
Description:gi_190938
Residue:37
Sequence:
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50022271
n/a
NameBDBM50022271
Synonyms:2-(3-Benzoylphenyl)propionic acid | 2-(3-benzoylphenyl)propanoic acid | 3-Benzoyl-alpha-methylbenzeneacetic acid | 3-Benzoylhydratropic acid | CHEMBL571 | Dexketoprofen trometamol | KETOPROFEN | L'Acide (benzoyl-3-phenyl)-2-propionique | Orudis (TN) | m-Benzoylhydratropic acid
TypeSmall organic molecule
Emp. Form.C16H14O3
Mol. Mass.254.2806
SMILESCC(C(O)=O)c1cccc(c1)C(=O)c1ccccc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: