Ki Summary

Reaction Details

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Target

Ras-related C3 botulinum toxin substrate 1

Ligand

BDBM50110164

Substrate/Competitor

n/a

Meas. Tech.

Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 wildtype

5110±n/a nM

Citation

PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 wildtype PubChem Bioassay(2009)[AID]

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Ras-related C3 botulinum toxin substrate 1

Name:

Ras-related C3 botulinum toxin substrate 1

Synonyms:

RAC1_MOUSE | Rac1 | Rac1 protein

Type:

PROTEIN

Mol. Mass.:

21455.91

Organism:

Mus musculus

Description:

EBI_101485

Residue:

192

Sequence:

MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR
DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP
PVKKRKRKCLLL

BDBM50110164

n/a

Name

BDBM50110164

Synonyms:

(Z)-2-(3-(4-(methylthio)benzylidene)-6-fluoro-2-methyl-3H-inden-1-yl)acetic acid | 2-(3-(4-(methylthio)benzylidene)-6-fluoro-2-methyl-3H-inden-1-yl)acetic acid | CHEMBL18797 | SULINDAC SULFIDE | Sulindac sulphide | [6-Fluoro-2-methyl-3-(4-methylsulfanyl-benzylidene)-3H-inden-1-yl]-acetic acid | cid_5352624 | {6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-meth-(E)-ylidene]-3H-inden-1-yl}-acetic acid | {6-Fluoro-2-methyl-3-[1-[4-(methyl-lambda*4*-sulfanyl)-phenyl]-meth-(E)-ylidene]-3H-inden-1-yl}-acetic acid

Type

Small organic molecule

Emp. Form.

C20H17FO2S

Mol. Mass.

340.411

SMILES

CSc1ccc(\C=C2\C(C)=C(CC(O)=O)c3cc(F)ccc23)cc1 |t:9|

Structure