| Reaction Details |
|---|
 | Report a problem with these data |
| Target | GTPase KRas [1-37] |
|---|
| Ligand | BDBM54694 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant |
|---|
| Ki | 560±n/a nM |
|---|
| Comments | Extracted from aid = 2043 and tid = 3 |
|---|
| Citation |  PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant PubChem Bioassay(2009)[AID] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| GTPase KRas [1-37] |
|---|
| Name: | GTPase KRas [1-37] |
|---|
| Synonyms: | ras protein |
|---|
| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 4034.04 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_190938 |
|---|
| Residue: | 37 |
|---|
| Sequence: | MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE
|
|
|
|---|
| BDBM54694 |
|---|
| n/a |
|---|
| Name | BDBM54694 |
|---|
| Synonyms: | 1-(2-nitrophenyl)-3-phenyl-2-propyn-1-one | 1-(2-nitrophenyl)-3-phenyl-prop-2-yn-1-one | 1-(2-nitrophenyl)-3-phenylprop-2-yn-1-one | UNM-0000306038 | cid_25227393 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H9NO3 |
|---|
| Mol. Mass. | 251.2369 |
|---|
| SMILES | [O-][N+](=O)c1ccccc1C(=O)C#Cc1ccccc1 |
|---|
| Structure | 
|
|---|
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