Reaction Details |
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Target | GTPase KRas [1-37] |
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Ligand | BDBM54606 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant |
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Ki | 10±n/a nM |
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Citation | PubChem, PC Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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GTPase KRas [1-37] |
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Name: | GTPase KRas [1-37] |
Synonyms: | ras protein |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 4034.04 |
Organism: | Homo sapiens (Human) |
Description: | gi_190938 |
Residue: | 37 |
Sequence: | MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE
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BDBM54606 |
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n/a |
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Name | BDBM54606 |
Synonyms: | 4-[3-(4-chlorophenyl)-5-phenyl-2-pyrazolin-1-yl]benzenesulfonamide | 4-[5-(4-chlorophenyl)-3-phenyl-3,4-dihydropyrazol-2-yl]benzenesulfonamide | UNM-0000305844 | cid_14199395 |
Type | Small organic molecule |
Emp. Form. | C21H18ClN3O2S |
Mol. Mass. | 411.905 |
SMILES | NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1ccccc1)c1ccc(Cl)cc1 |c:12| |
Structure |
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