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TargetRas-related C3 botulinum toxin substrate 1
LigandBDBM54552
Substrate/Competitorn/a
Meas. Tech.Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 activated mutant
Ki 180±n/a nM
Citation PubChem, PC Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 activated mutant PubChem Bioassay(2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Ras-related C3 botulinum toxin substrate 1
Name:Ras-related C3 botulinum toxin substrate 1
Synonyms:RAC1_MOUSE | Rac1 | Rac1 protein
Type:PROTEIN
Mol. Mass.:21455.91
Organism:Mus musculus
Description:EBI_101485
Residue:192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR
DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP
PVKKRKRKCLLL
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BDBM54552
n/a
NameBDBM54552
Synonyms:1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-[3-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]-1-propanone | 1-[4-(2,5-dimethylphenyl)piperazin-1-yl]-3-[3-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]propan-1-one | 1-[4-(2,5-dimethylphenyl)piperazino]-3-[3-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]propan-1-one | KUC103363N | UNM-0000306073 | cid_42596901
TypeSmall organic molecule
Emp. Form.C24H25F3N4O2
Mol. Mass.458.4761
SMILESCc1ccc(C)c(c1)N1CCN(CC1)C(=O)CCc1nc(no1)-c1ccc(cc1)C(F)(F)F
Structure
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