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TargetHematopoietic protein-tyrosine phosphatase (HEPTP)
LigandBDBM46133
Substrate/Competitorn/a
Meas. Tech.MOA HePTP Fluorescent secondary assay for identification of redox-state modulating compounds
IC50 180±n/a nM
Citation PubChem PC MOA HePTP Fluorescent secondary assay for identification of redox-state modulating compounds PubChem Bioassay (2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Hematopoietic protein-tyrosine phosphatase (HEPTP)
Name:Hematopoietic protein-tyrosine phosphatase (HEPTP)
Synonyms:He-PTP | Hematopoietic protein-tyrosine phosphatase | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:Protein
Mol. Mass.:40530.79
Organism:Homo sapiens (Human)
Description:P35236
Residue:360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
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  Blast E-value cutoff:
BDBM46133
n/a
NameBDBM46133
Synonyms:(7Z)-3-bromanyl-7-[(2-chlorophenyl)methylidene]-[1,3]thiazolo[4,5]imidazo[1,2-b]pyridin-8-one | (7Z)-3-bromo-7-(2-chlorobenzylidene)thiazolo[4,5]imidazo[1,2-b]pyridin-8-one | (7Z)-3-bromo-7-[(2-chlorophenyl)methylidene]-8-thiazolo[4,5]imidazo[1,2-b]pyridinone | (7Z)-3-bromo-7-[(2-chlorophenyl)methylidene]-[1,3]thiazolo[4,5]imidazo[1,2-b]pyridin-8-one | MLS-0091944.0001 | cid_2258411
TypeSmall organic molecule
Emp. Form.C15H7BrClN3OS
Mol. Mass.392.658
SMILESClc1ccccc1\C=c1/sc2nc3cc(Br)cnc3n2c1=O
Structure
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