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TargetTyrosine-protein phosphatase non-receptor type 7
LigandBDBM46222
Substrate/Competitorn/a
Meas. Tech.MOA HePTP Fluorescent secondary assay for identification of redox-state modulating compounds
IC50 195±n/a nM
Citation PubChem, PC MOA HePTP Fluorescent secondary assay for identification of redox-state modulating compounds PubChem Bioassay(2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Tyrosine-protein phosphatase non-receptor type 7
Name:Tyrosine-protein phosphatase non-receptor type 7
Synonyms:He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:Protein
Mol. Mass.:40530.79
Organism:Homo sapiens (Human)
Description:P35236
Residue:360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
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  Blast E-value cutoff:
BDBM46222
n/a
NameBDBM46222
Synonyms:3-(3-chloranyl-4-methoxy-phenyl)-1-(3-methylbutyl)-1-(1-propan-2-ylpiperidin-4-yl)thiourea | 3-(3-chloro-4-methoxy-phenyl)-1-isoamyl-1-(1-isopropyl-4-piperidyl)thiourea | 3-(3-chloro-4-methoxyphenyl)-1-(3-methylbutyl)-1-(1-propan-2-yl-4-piperidinyl)thiourea | 3-(3-chloro-4-methoxyphenyl)-1-(3-methylbutyl)-1-(1-propan-2-ylpiperidin-4-yl)thiourea | MLS-0330044.0001 | cid_24761488
TypeSmall organic molecule
Emp. Form.C21H34ClN3OS
Mol. Mass.412.032
SMILESCOc1ccc(NC(=S)N(CCC(C)C)C2CCN(CC2)C(C)C)cc1Cl
Structure
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