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TargetHematopoietic protein-tyrosine phosphatase (HEPTP)
LigandBDBM46252
Substrate/Competitorn/a
Meas. Tech.MOA HePTP Fluorescent secondary assay for identification of redox-state modulating compounds
IC50 665±n/a nM
Citation PubChem PC MOA HePTP Fluorescent secondary assay for identification of redox-state modulating compounds PubChem Bioassay (2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Hematopoietic protein-tyrosine phosphatase (HEPTP)
Name:Hematopoietic protein-tyrosine phosphatase (HEPTP)
Synonyms:He-PTP | Hematopoietic protein-tyrosine phosphatase | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:Protein
Mol. Mass.:40530.79
Organism:Homo sapiens (Human)
Description:P35236
Residue:360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
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  Blast E-value cutoff:
BDBM46252
n/a
NameBDBM46252
Synonyms:(4E)-2-methoxy-4-[[(phenylmethyl)amino]-sulfanyl-methylidene]cyclohexa-2,5-dien-1-one | (4E)-4-[(benzylamino)-mercapto-methylene]-2-methoxy-cyclohexa-2,5-dien-1-one | (4E)-4-[(benzylamino)-sulfanylmethylidene]-2-methoxycyclohexa-2,5-dien-1-one | (4E)-4-[mercapto-[(phenylmethyl)amino]methylidene]-2-methoxy-1-cyclohexa-2,5-dienone | MLS-0412121.0001 | cid_20110352
TypeSmall organic molecule
Emp. Form.C15H15NO2S
Mol. Mass.273.35
SMILESCOc1cc(ccc1O)C(=S)NCc1ccccc1
Structure
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