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TargetHematopoietic protein-tyrosine phosphatase (HEPTP)
LigandBDBM46281
Substrate/Competitorn/a
Meas. Tech.MOA HePTP Fluorescent secondary assay for identification of redox-state modulating compounds
IC50 1070±n/a nM
Citation PubChem PC MOA HePTP Fluorescent secondary assay for identification of redox-state modulating compounds PubChem Bioassay (2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Hematopoietic protein-tyrosine phosphatase (HEPTP)
Name:Hematopoietic protein-tyrosine phosphatase (HEPTP)
Synonyms:He-PTP | Hematopoietic protein-tyrosine phosphatase | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:Protein
Mol. Mass.:40530.79
Organism:Homo sapiens (Human)
Description:P35236
Residue:360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
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  Blast E-value cutoff:
BDBM46281
n/a
NameBDBM46281
Synonyms:2-[4-[(Z)-[2-(4-fluoroanilino)-4-keto-2-thiazolin-5-ylidene]methyl]phenoxy]acetic acid methyl ester | 2-[4-[(Z)-[2-(4-fluoroanilino)-4-oxo-5-thiazolylidene]methyl]phenoxy]acetic acid methyl ester | MLS-0425606.0001 | cid_5766720 | methyl 2-[4-[(Z)-[2-(4-fluoroanilino)-4-oxo-1,3-thiazol-5-ylidene]methyl]phenoxy]acetate | methyl 2-[4-[(Z)-[2-[(4-fluorophenyl)amino]-4-oxidanylidene-1,3-thiazol-5-ylidene]methyl]phenoxy]ethanoate
TypeSmall organic molecule
Emp. Form.C19H15FN2O4S
Mol. Mass.386.397
SMILESCOC(=O)COc1ccc(C=C2SC(Nc3ccc(F)cc3)=NC2=O)cc1 |w:10.9,c:22|
Structure
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