Reaction Details |
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Target | Bcl-2-related protein A1 |
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Ligand | BDBM30741 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1 |
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EC50 | 4920±n/a nM |
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Citation | PubChem, PC Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1 PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Bcl-2-related protein A1 |
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Name: | Bcl-2-related protein A1 |
Synonyms: | B2LA1_HUMAN | BCL2A1 | BCL2L5 | BFL1 | Bcl-2-like protein 5 | GRS | HBPA1 | Hemopoietic-specific early response protein | Protein BFL-1 | Protein GRS |
Type: | Apoptosis regulator protein |
Mol. Mass.: | 20130.01 |
Organism: | Homo sapiens (Human) |
Description: | n/a |
Residue: | 175 |
Sequence: | MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVN
VVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISY
FVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC
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BDBM30741 |
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n/a |
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Name | BDBM30741 |
Synonyms: | 2-amino-6-(4-chlorophenyl)-4-(5-methyl-3-furanyl)-3-pyridinecarbonitrile | 2-amino-6-(4-chlorophenyl)-4-(5-methyl-3-furyl)nicotinonitrile | 2-amino-6-(4-chlorophenyl)-4-(5-methylfuran-3-yl)pyridine-3-carbonitrile | 2-azanyl-6-(4-chlorophenyl)-4-(5-methylfuran-3-yl)pyridine-3-carbonitrile | MLS000036685 | SMR000041039 | cid_660120 |
Type | Small organic molecule |
Emp. Form. | C17H12ClN3O |
Mol. Mass. | 309.75 |
SMILES | Cc1cc(co1)-c1cc(nc(N)c1C#N)-c1ccc(Cl)cc1 |
Structure |
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