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Reaction Details
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TargetCore protein
LigandBDBM54962
Substrate/Competitorn/a
Meas. Tech.TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization.
IC50>49751±n/a nM
Citation PubChem, PC TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization. PubChem Bioassay(2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Core protein
Name:Core protein
Synonyms:n/a
Type:Enzyme Catalytic Domain
Mol. Mass.:14237.71
Organism:Hepatitis C virus
Description:gi_83779224
Residue:126
Sequence:
MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRG
RRQPIPKDQRTTGKSWGKPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPNDPRHRSRNVG
KVIDTL
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  Blast E-value cutoff:
BDBM54962
n/a
NameBDBM54962
Synonyms:2,6-bis(azanyl)-4-(2-methylthiophen-3-yl)-4H-thiopyran-3,5-dicarbonitrile | 2,6-diamino-4-(2-methyl-3-thienyl)-4H-thiopyran-3,5-dicarbonitrile | 2,6-diamino-4-(2-methyl-3-thiophenyl)-4H-thiopyran-3,5-dicarbonitrile | 2,6-diamino-4-(2-methylthiophen-3-yl)-4H-thiopyran-3,5-dicarbonitrile | MLS000027965 | SMR000039073 | cid_658074
TypeSmall organic molecule
Emp. Form.C12H10N4S2
Mol. Mass.274.365
SMILESCc1sccc1C1C(C#N)C(=N)SC(=N)C1C#N
Structure
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