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Reaction Details
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TargetCore protein
LigandBDBM54965
Substrate/Competitorn/a
Meas. Tech.TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization.
IC50>49751±n/a nM
Citation PubChem, PC TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization. PubChem Bioassay(2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Core protein
Name:Core protein
Synonyms:n/a
Type:Enzyme Catalytic Domain
Mol. Mass.:14237.71
Organism:Hepatitis C virus
Description:gi_83779224
Residue:126
Sequence:
MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRG
RRQPIPKDQRTTGKSWGKPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPNDPRHRSRNVG
KVIDTL
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  Blast E-value cutoff:
BDBM54965
n/a
NameBDBM54965
Synonyms:1-(2,3-dihydroindol-1-yl)-2-[(5-ethyl-1,3,4-thiadiazol-2-yl)amino]ethanone | 2-[(5-ethyl-1,3,4-thiadiazol-2-yl)amino]-1-indolin-1-yl-ethanone | MLS000096536 | SMR000062393 | cid_2997524
TypeSmall organic molecule
Emp. Form.C14H16N4OS
Mol. Mass.288.368
SMILESCCc1nnc(NCC(=O)N2CCc3ccccc23)s1
Structure
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