Ki Summary

Reaction Details

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Target

Core protein

Ligand

BDBM50019

Substrate/Competitor

n/a

Meas. Tech.

TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization.

IC50

>49751±n/a nM

Citation

PubChem, PC TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization. PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Core protein

Name:

Core protein

Synonyms:

n/a

Type:

Enzyme Catalytic Domain

Mol. Mass.:

14237.71

Organism:

Hepatitis C virus

Description:

gi_83779224

Residue:

126

Sequence:

MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRG
RRQPIPKDQRTTGKSWGKPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPNDPRHRSRNVG
KVIDTL

BDBM50019

n/a

Name

BDBM50019

Synonyms:

2-(1,3-dihydrobenzimidazol-2-ylidene)-4-[(5,7-dimethyl-[1,2,4]triazolo[4,3-a]pyrimidin-3-yl)sulfanyl]-3-oxidanylidene-butanenitrile | 2-(1,3-dihydrobenzimidazol-2-ylidene)-4-[(5,7-dimethyl-[1,2,4]triazolo[4,3-a]pyrimidin-3-yl)sulfanyl]-3-oxobutanenitrile | 2-(1,3-dihydrobenzimidazol-2-ylidene)-4-[(5,7-dimethyl-[1,2,4]triazolo[4,3-a]pyrimidin-3-yl)thio]-3-keto-butyronitrile | 2-(1,3-dihydrobenzimidazol-2-ylidene)-4-[(5,7-dimethyl-[1,2,4]triazolo[4,3-a]pyrimidin-3-yl)thio]-3-oxobutanenitrile | MLS000057091 | SMR000064178 | cid_5643743

Type

Small organic molecule

Emp. Form.

C18H15N7OS

Mol. Mass.

377.423

SMILES

Cc1cc(C)n2c(SCC(=O)C(C#N)c3nc4ccccc4[nH]3)nnc2n1

Structure