Ki Summary

Reaction Details

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Target

Core protein

Ligand

BDBM34295

Substrate/Competitor

n/a

Meas. Tech.

TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization.

IC50

>49751±n/a nM

Citation

PubChem, PC TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization. PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Core protein

Name:

Core protein

Synonyms:

n/a

Type:

Enzyme Catalytic Domain

Mol. Mass.:

14237.71

Organism:

Hepatitis C virus

Description:

gi_83779224

Residue:

126

Sequence:

MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRG
RRQPIPKDQRTTGKSWGKPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPNDPRHRSRNVG
KVIDTL

BDBM34295

n/a

Name

BDBM34295

Synonyms:

6-keto-8-(5-methyl-2-furyl)-3-(m-tolyl)-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrile | 8-(5-methyl-2-furanyl)-3-(3-methylphenyl)-6-oxo-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrile | 8-(5-methylfuran-2-yl)-3-(3-methylphenyl)-6-oxidanylidene-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrile | 8-(5-methylfuran-2-yl)-3-(3-methylphenyl)-6-oxo-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrile | MLS000080648 | SMR000035447 | cid_666162

Type

Small organic molecule

Emp. Form.

C20H19N3O2S

Mol. Mass.

365.449

SMILES

Cc1ccc(o1)C1CC(=O)N2CN(CSC2=C1C#N)c1cccc(C)c1 |c:17|

Structure