Ki Summary

Reaction Details

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Target

Core protein

Ligand

BDBM49371

Substrate/Competitor

n/a

Meas. Tech.

TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization.

IC50

>49751±n/a nM

Citation

PubChem, PC TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization. PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Core protein

Name:

Core protein

Synonyms:

n/a

Type:

Enzyme Catalytic Domain

Mol. Mass.:

14237.71

Organism:

Hepatitis C virus

Description:

gi_83779224

Residue:

126

Sequence:

MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRG
RRQPIPKDQRTTGKSWGKPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPNDPRHRSRNVG
KVIDTL

BDBM49371

n/a

Name

BDBM49371

Synonyms:

1,4,5,6-Tetrahydro-cyclopentapyrazole-3-carboxylic acid (2-bromo-3-phenyl-allylidene)-hydrazide | MLS000526009 | N-[(E)-[(E)-2-bromo-3-phenyl-prop-2-enylidene]amino]-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxamide | N-[[(E)-2-bromo-3-phenyl-prop-2-enylidene]amino]-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxamide | N-[[(Z)-2-bromanyl-3-phenyl-prop-2-enylidene]amino]-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxamide | N-[[(Z)-2-bromo-3-phenyl-prop-2-enylidene]amino]-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxamide | N-[[(Z)-2-bromo-3-phenylprop-2-enylidene]amino]-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxamide | SMR000116483 | cid_1097667

Type

Small organic molecule

Emp. Form.

C16H15BrN4O

Mol. Mass.

359.22

SMILES

BrC(C=NNC(=O)c1[nH]nc2CCCc12)=Cc1ccccc1 |w:3.3,15.17|

Structure