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Reaction Details
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TargetCore protein
LigandBDBM32280
Substrate/Competitorn/a
Meas. Tech.TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization.
IC50>49751±n/a nM
Citation PubChem, PC TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization. PubChem Bioassay(2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Core protein
Name:Core protein
Synonyms:n/a
Type:Enzyme Catalytic Domain
Mol. Mass.:14237.71
Organism:Hepatitis C virus
Description:gi_83779224
Residue:126
Sequence:
MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRG
RRQPIPKDQRTTGKSWGKPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPNDPRHRSRNVG
KVIDTL
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  Blast E-value cutoff:
BDBM32280
n/a
NameBDBM32280
Synonyms:MLS000534769 | N-(4-acetylphenyl)-2,3-bis(2-furanyl)-6-quinoxalinecarboxamide | N-(4-acetylphenyl)-2,3-bis(2-furyl)quinoxaline-6-carboxamide | N-(4-acetylphenyl)-2,3-bis(furan-2-yl)quinoxaline-6-carboxamide | N-(4-acetylphenyl)-2,3-di-2-furyl-6-quinoxalinecarboxamide | N-(4-ethanoylphenyl)-2,3-bis(furan-2-yl)quinoxaline-6-carboxamide | SMR000142225 | cid_1331726
TypeSmall organic molecule
Emp. Form.C25H17N3O4
Mol. Mass.423.4202
SMILESCC(=O)c1ccc(NC(=O)c2ccc3nc(-c4ccco4)c(nc3c2)-c2ccco2)cc1
Structure
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