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Reaction Details
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TargetCore protein
LigandBDBM40714
Substrate/Competitorn/a
Meas. Tech.TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization.
IC50>49751±n/a nM
Citation PubChem, PC TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization. PubChem Bioassay(2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Core protein
Name:Core protein
Synonyms:n/a
Type:Enzyme Catalytic Domain
Mol. Mass.:14237.71
Organism:Hepatitis C virus
Description:gi_83779224
Residue:126
Sequence:
MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRG
RRQPIPKDQRTTGKSWGKPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPNDPRHRSRNVG
KVIDTL
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  Blast E-value cutoff:
BDBM40714
n/a
NameBDBM40714
Synonyms:2-(2-furanyl)-4-quinolinecarboxylic acid [2-[(2-methoxyphenyl)methylamino]-2-oxoethyl] ester | 2-(2-furyl)cinchoninic acid [2-keto-2-(o-anisylamino)ethyl] ester | MLS000565742 | SMR000152918 | [2-[(2-methoxyphenyl)methylamino]-2-oxidanylidene-ethyl] 2-(furan-2-yl)quinoline-4-carboxylate | [2-[(2-methoxyphenyl)methylamino]-2-oxoethyl] 2-(furan-2-yl)quinoline-4-carboxylate | cid_2092254
TypeSmall organic molecule
Emp. Form.C24H20N2O5
Mol. Mass.416.426
SMILESCOc1ccccc1CNC(=O)COC(=O)c1cc(nc2ccccc12)-c1ccco1
Structure
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