Reaction Details |
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Target | Core protein |
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Ligand | BDBM54999 |
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Substrate/Competitor | n/a |
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Meas. Tech. | TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization. |
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IC50 | 48568±n/a nM |
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Citation | PubChem, PC TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization. PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Core protein |
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Name: | Core protein |
Synonyms: | n/a |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 14237.71 |
Organism: | Hepatitis C virus |
Description: | gi_83779224 |
Residue: | 126 |
Sequence: | MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRG
RRQPIPKDQRTTGKSWGKPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPNDPRHRSRNVG
KVIDTL
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BDBM54999 |
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n/a |
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Name | BDBM54999 |
Synonyms: | 5,6-dihydro-4H-cyclopenta[b]thiophene-2-carboxylic acid [2-[(6-amino-1-benzyl-2,4-diketo-pyrimidin-5-yl)-(2-methoxyethyl)amino]-2-keto-ethyl] ester | 5,6-dihydro-4H-cyclopenta[b]thiophene-2-carboxylic acid [2-[[6-amino-2,4-dioxo-1-(phenylmethyl)-5-pyrimidinyl]-(2-methoxyethyl)amino]-2-oxoethyl] ester | MLS001080179 | SMR000711361 | [2-[(6-amino-1-benzyl-2,4-dioxopyrimidin-5-yl)-(2-methoxyethyl)amino]-2-oxoethyl] 5,6-dihydro-4H-cyclopenta[b]thiophene-2-carboxylate | [2-[[6-azanyl-2,4-bis(oxidanylidene)-1-(phenylmethyl)pyrimidin-5-yl]-(2-methoxyethyl)amino]-2-oxidanylidene-ethyl] 5,6-dihydro-4H-cyclopenta[b]thiophene-2-carboxylate | cid_24979394 |
Type | Small organic molecule |
Emp. Form. | C24H26N4O6S |
Mol. Mass. | 498.551 |
SMILES | COCCN(C(=O)COC(=O)c1cc2CCCc2s1)c1c(N)n(Cc2ccccc2)c(=O)[nH]c1=O |
Structure |
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