BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
Target2'-phosphotransferase
LigandBDBM55012
Substrate/Competitorn/a
Meas. Tech.Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1).
IC50>55688±n/a nM
Citation PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1). PubChem Bioassay(2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
2'-phosphotransferase
Name:2'-phosphotransferase
Synonyms:likely tRNA 2'-phosphotransferase
Type:Enzyme Catalytic Domain
Mol. Mass.:23631.37
Organism:Candida albicans SC5314
Description:gi_68476498
Residue:207
Sequence:
MPPPDKARRDVLISKALSYLLRHGAEKEKLSIDDQGYVKISDVLSHQRLKSLKTTRDDIN
RIVQENDKKRFTIKDDMICANQGHSLKAVKNDNLTPMTVDELNQLRIYHGTYRTKLPLIK
SSGGLSKMNRNHIHFTCEQYSTCSGIRYNANVLIYINASKCIEHGIVFYKSLNNVILTSG
DKDGKLSWEFIDRIVGLDGNEINKEQV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM55012
n/a
NameBDBM55012
Synonyms:(5Z)-1-(2-furanylmethyl)-5-[[1-[2-(4-methylphenoxy)ethyl]-2-pyrrolyl]methylidene]-1,3-diazinane-2,4,6-trione | (5Z)-1-(2-furfuryl)-5-[[1-[2-(4-methylphenoxy)ethyl]pyrrol-2-yl]methylene]barbituric acid | (5Z)-1-(furan-2-ylmethyl)-5-[[1-[2-(4-methylphenoxy)ethyl]pyrrol-2-yl]methylidene]-1,3-diazinane-2,4,6-trione | 1-Furan-2-ylmethyl-5-[1-[1-(2-p-tolyloxy-ethyl)-1H-pyrrol-2-yl]-meth-(Z)-ylidene]-pyrimidine-2,4,6-trione | MLS000769050 | SMR000433820 | cid_1852376
TypeSmall organic molecule
Emp. Form.C23H21N3O5
Mol. Mass.419.4299
SMILESCc1ccc(OCCn2cccc2\C=C2\C(=O)NC(=O)N(Cc3ccco3)C2=O)cc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: