Reaction Details |
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Target | 2'-phosphotransferase |
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Ligand | BDBM55012 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1). |
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IC50 | >55688±n/a nM |
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Citation | PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1). PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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2'-phosphotransferase |
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Name: | 2'-phosphotransferase |
Synonyms: | likely tRNA 2'-phosphotransferase |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 23631.37 |
Organism: | Candida albicans SC5314 |
Description: | gi_68476498 |
Residue: | 207 |
Sequence: | MPPPDKARRDVLISKALSYLLRHGAEKEKLSIDDQGYVKISDVLSHQRLKSLKTTRDDIN
RIVQENDKKRFTIKDDMICANQGHSLKAVKNDNLTPMTVDELNQLRIYHGTYRTKLPLIK
SSGGLSKMNRNHIHFTCEQYSTCSGIRYNANVLIYINASKCIEHGIVFYKSLNNVILTSG
DKDGKLSWEFIDRIVGLDGNEINKEQV
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BDBM55012 |
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n/a |
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Name | BDBM55012 |
Synonyms: | (5Z)-1-(2-furanylmethyl)-5-[[1-[2-(4-methylphenoxy)ethyl]-2-pyrrolyl]methylidene]-1,3-diazinane-2,4,6-trione | (5Z)-1-(2-furfuryl)-5-[[1-[2-(4-methylphenoxy)ethyl]pyrrol-2-yl]methylene]barbituric acid | (5Z)-1-(furan-2-ylmethyl)-5-[[1-[2-(4-methylphenoxy)ethyl]pyrrol-2-yl]methylidene]-1,3-diazinane-2,4,6-trione | 1-Furan-2-ylmethyl-5-[1-[1-(2-p-tolyloxy-ethyl)-1H-pyrrol-2-yl]-meth-(Z)-ylidene]-pyrimidine-2,4,6-trione | MLS000769050 | SMR000433820 | cid_1852376 |
Type | Small organic molecule |
Emp. Form. | C23H21N3O5 |
Mol. Mass. | 419.4299 |
SMILES | Cc1ccc(OCCn2cccc2\C=C2\C(=O)NC(=O)N(Cc3ccco3)C2=O)cc1 |
Structure |
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