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Target2'-phosphotransferase
LigandBDBM52921
Substrate/Competitorn/a
Meas. Tech.Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1).
IC50>55688±n/a nM
Citation PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1). PubChem Bioassay(2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
2'-phosphotransferase
Name:2'-phosphotransferase
Synonyms:likely tRNA 2'-phosphotransferase
Type:Enzyme Catalytic Domain
Mol. Mass.:23631.37
Organism:Candida albicans SC5314
Description:gi_68476498
Residue:207
Sequence:
MPPPDKARRDVLISKALSYLLRHGAEKEKLSIDDQGYVKISDVLSHQRLKSLKTTRDDIN
RIVQENDKKRFTIKDDMICANQGHSLKAVKNDNLTPMTVDELNQLRIYHGTYRTKLPLIK
SSGGLSKMNRNHIHFTCEQYSTCSGIRYNANVLIYINASKCIEHGIVFYKSLNNVILTSG
DKDGKLSWEFIDRIVGLDGNEINKEQV
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  Blast E-value cutoff:
BDBM52921
n/a
NameBDBM52921
Synonyms:(5E)-5-(3-ethoxy-4-hydroxy-benzylidene)-1-[2-(4-fluorophenyl)ethyl]barbituric acid | (5E)-5-[(3-ethoxy-4-hydroxyphenyl)methylidene]-1-[2-(4-fluorophenyl)ethyl]-1,3-diazinane-2,4,6-trione | (5E)-5-[(3-ethoxy-4-oxidanyl-phenyl)methylidene]-1-[2-(4-fluorophenyl)ethyl]-1,3-diazinane-2,4,6-trione | 5-[1-(3-Ethoxy-4-hydroxy-phenyl)-meth-(E)-ylidene]-1-[2-(4-fluoro-phenyl)-ethyl]-pyrimidine-2,4,6-trione | MLS000778165 | SMR000414559 | cid_5514790
TypeSmall organic molecule
Emp. Form.C21H19FN2O5
Mol. Mass.398.3844
SMILESCCOc1cc(\C=C2/C(=O)NC(=O)N(CCc3ccc(F)cc3)C2=O)ccc1O
Structure
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