| Reaction Details |
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 | Report a problem with these data |
| Target | Guanyl-specific ribonuclease T1 |
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| Ligand | BDBM46749 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for inhibitors of tRNA 2'-phosphotransferase (TPT1): fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of RNAse T1. |
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| IC50 | 2133±n/a nM |
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| Citation |  PubChem, PC Counterscreen for inhibitors of tRNA 2'-phosphotransferase (TPT1): fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of RNAse T1. PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Guanyl-specific ribonuclease T1 |
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| Name: | Guanyl-specific ribonuclease T1 |
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| Synonyms: | RNT1_ASPOR | rntA | unnamed protein product |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 13952.57 |
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| Organism: | Aspergillus oryzae |
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| Description: | gi_83774548 |
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| Residue: | 130 |
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| Sequence: | MMYSKLLTLTTLLLPTALALPSLVERACDYTCGSNCYSSSDVSTAQAAGYQLHEDGETVG
SNSYPHKYNNYEGFDFSVSSPYYEWPILSSGDVYSGGSPGADRVVFNENNQLAGVITHTG
ASGNNFVECT
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|
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| BDBM46749 |
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| n/a |
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| Name | BDBM46749 |
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| Synonyms: | 1-acetyl-3-(2,6-dimethyl-4-pyranylidene)-2-indolone | 1-acetyl-3-(2,6-dimethyl-4H-pyran-4-ylidene)-1,3-dihydro-2H-indol-2-one | 1-acetyl-3-(2,6-dimethylpyran-4-ylidene)indol-2-one | 1-acetyl-3-(2,6-dimethylpyran-4-ylidene)oxindole | 3-(2,6-dimethylpyran-4-ylidene)-1-ethanoyl-indol-2-one | MLS000043288 | SMR000019908 | cid_697318 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H15NO3 |
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| Mol. Mass. | 281.3059 |
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| SMILES | [#6]-[#6](=O)-[#7]-1-[#6](=O)\[#6](-c2ccccc-12)=[#6]-1\[#6]=[#6](-[#6])-[#8]-[#6](-[#6])=[#6]-1 |c:21,t:16| |
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| Structure | 
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