Reaction Details |
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Target | Guanyl-specific ribonuclease T1 |
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Ligand | BDBM55011 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Counterscreen for inhibitors of tRNA 2'-phosphotransferase (TPT1): fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of RNAse T1. |
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IC50 | >55688±n/a nM |
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Citation | PubChem, PC Counterscreen for inhibitors of tRNA 2'-phosphotransferase (TPT1): fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of RNAse T1. PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Guanyl-specific ribonuclease T1 |
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Name: | Guanyl-specific ribonuclease T1 |
Synonyms: | RNT1_ASPOR | rntA | unnamed protein product |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 13952.57 |
Organism: | Aspergillus oryzae |
Description: | gi_83774548 |
Residue: | 130 |
Sequence: | MMYSKLLTLTTLLLPTALALPSLVERACDYTCGSNCYSSSDVSTAQAAGYQLHEDGETVG
SNSYPHKYNNYEGFDFSVSSPYYEWPILSSGDVYSGGSPGADRVVFNENNQLAGVITHTG
ASGNNFVECT
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BDBM55011 |
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n/a |
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Name | BDBM55011 |
Synonyms: | (5E)-1-(4-methylphenyl)-5-[(5-nitro-2-furanyl)methylidene]-1,3-diazinane-2,4,6-trione | (5E)-1-(4-methylphenyl)-5-[(5-nitro-2-furyl)methylene]pyrimidine-2,4,6(1H,3H,5H)-trione | (5E)-1-(4-methylphenyl)-5-[(5-nitrofuran-2-yl)methylidene]-1,3-diazinane-2,4,6-trione | (5E)-5-[(5-nitro-2-furyl)methylene]-1-(p-tolyl)barbituric acid | MLS000723838 | SMR000305433 | cid_2201932 |
Type | Small organic molecule |
Emp. Form. | C16H11N3O6 |
Mol. Mass. | 341.275 |
SMILES | Cc1ccc(cc1)-n1c(=O)[nH]c([O-])c([CH+]c2ccc(o2)[N+]([O-])=O)c1=O |
Structure |
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