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TargetGuanyl-specific ribonuclease T1
LigandBDBM50729
Substrate/Competitorn/a
Meas. Tech.Counterscreen for inhibitors of tRNA 2'-phosphotransferase (TPT1): fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of RNAse T1.
IC50 18474±n/a nM
Citation PubChem, PC Counterscreen for inhibitors of tRNA 2'-phosphotransferase (TPT1): fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of RNAse T1. PubChem Bioassay(2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Guanyl-specific ribonuclease T1
Name:Guanyl-specific ribonuclease T1
Synonyms:RNT1_ASPOR | rntA | unnamed protein product
Type:Enzyme Catalytic Domain
Mol. Mass.:13952.57
Organism:Aspergillus oryzae
Description:gi_83774548
Residue:130
Sequence:
MMYSKLLTLTTLLLPTALALPSLVERACDYTCGSNCYSSSDVSTAQAAGYQLHEDGETVG
SNSYPHKYNNYEGFDFSVSSPYYEWPILSSGDVYSGGSPGADRVVFNENNQLAGVITHTG
ASGNNFVECT
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  Blast E-value cutoff:
BDBM50729
n/a
NameBDBM50729
Synonyms:MLS000778639 | N-[(5Z)-5-[(E)-3-(2-furanyl)prop-2-enylidene]-4-oxo-2-sulfanylidene-3-thiazolidinyl]benzenesulfonamide | N-[(5Z)-5-[(E)-3-(2-furyl)prop-2-enylidene]-4-keto-2-thioxo-thiazolidin-3-yl]benzenesulfonamide | N-[(5Z)-5-[(E)-3-(furan-2-yl)prop-2-enylidene]-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-3-yl]benzenesulfonamide | N-[(5Z)-5-[(E)-3-(furan-2-yl)prop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]benzenesulfonamide | N-{5-[(E)-3-Furan-2-yl-prop-2-en-(Z)-ylidene]-4-oxo-2-thioxo-thiazolidin-3-yl}-benzenesulfonamide | SMR000415433 | cid_6393804
TypeSmall organic molecule
Emp. Form.C16H12N2O4S3
Mol. Mass.392.472
SMILESO=C1N(NS(=O)(=O)c2ccccc2)C(=S)S\C1=C/C=C/c1ccco1
Structure
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