| Reaction Details |
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 | Report a problem with these data |
| Target | Guanyl-specific ribonuclease T1 |
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| Ligand | BDBM51785 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for inhibitors of tRNA 2'-phosphotransferase (TPT1): fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of RNAse T1. |
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| IC50 | >55688±n/a nM |
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| Citation |  PubChem, PC Counterscreen for inhibitors of tRNA 2'-phosphotransferase (TPT1): fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of RNAse T1. PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Guanyl-specific ribonuclease T1 |
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| Name: | Guanyl-specific ribonuclease T1 |
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| Synonyms: | RNT1_ASPOR | rntA | unnamed protein product |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 13952.57 |
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| Organism: | Aspergillus oryzae |
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| Description: | gi_83774548 |
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| Residue: | 130 |
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| Sequence: | MMYSKLLTLTTLLLPTALALPSLVERACDYTCGSNCYSSSDVSTAQAAGYQLHEDGETVG
SNSYPHKYNNYEGFDFSVSSPYYEWPILSSGDVYSGGSPGADRVVFNENNQLAGVITHTG
ASGNNFVECT
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| BDBM51785 |
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| n/a |
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| Name | BDBM51785 |
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| Synonyms: | (5E)-1-(2,5-dimethoxyphenyl)-5-(2-furanylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione | (5E)-1-(2,5-dimethoxyphenyl)-5-(2-furfurylidene)-2-thioxo-hexahydropyrimidine-4,6-quinone | (5E)-1-(2,5-dimethoxyphenyl)-5-(2-furylmethylene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione | (5E)-1-(2,5-dimethoxyphenyl)-5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione | MLS001197216 | SMR000555410 | cid_1608674 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H14N2O5S |
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| Mol. Mass. | 358.368 |
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| SMILES | COc1ccc(OC)c(c1)N1C(=S)NC(=O)C(=Cc2ccco2)C1=O |w:17.18| |
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| Structure | 
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