| Reaction Details |
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 | Report a problem with these data |
| Target | Metabotropic glutamate receptor 4 [Q124R] |
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| Ligand | BDBM50293734 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Modulation of the Metabotropic Glutamate Receptor mGluR4: Rat PAM Potency |
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| EC50 | 3370±n/a nM |
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| Citation |  PubChem, PC Modulation of the Metabotropic Glutamate Receptor mGluR4: Rat PAM Potency PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Metabotropic glutamate receptor 4 [Q124R] |
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| Name: | Metabotropic glutamate receptor 4 [Q124R] |
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| Synonyms: | GRM4_RAT | Gprc1d | Grm4 | Mglur4 | glutamate receptor, metabotropic 4 precursor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 101878.86 |
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| Organism: | Rattus norvegicus |
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| Description: | gi_12083595 |
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| Residue: | 912 |
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| Sequence: | MSGKGGWAWWWARLPLCLLLSLYAPWVPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGR
GSEGKACGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSL
TFVRALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYA
STAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTLASEGSYGESGVEAFIQ
KSRENGGVCIAQSVKIPREPKTGEFDKIIKRLLETSNARGIIIFANEDDIRRVLEAARRA
NQTGHFFWMGSDSWGSKSAPVLRLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNI
WFAEFWEDNFHCKLSRHALKKGSHIKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHAL
HAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQY
QLRNGSAEYKVIGSWTDHLHLRIERMQWPGSGQQLPRSICSLPCQPGERKKTVKGMACCW
HCEPCTGYQYQVDRYTCKTCPYDMRPTENRTSCQPIPIVKLEWDSPWAVLPLFLAVVGIA
ATLFVVVTFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLG
LGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFILISLQLLGICVWFVV
DPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPET
FNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMP
KVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLETPALAT
KQTYVTYTNHAI
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| BDBM50293734 |
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| n/a |
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| Name | BDBM50293734 |
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| Synonyms: | CHEMBL560021 | N-(3,4-dichlorophenyl)pyrimidine-4-carboxamide | cid_44191099 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H7Cl2N3O |
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| Mol. Mass. | 268.099 |
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| SMILES | Clc1ccc(NC(=O)c2ccncn2)cc1Cl |
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| Structure | 
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