Ki Summary

Reaction Details

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Target

Metabotropic glutamate receptor 4 [Q124R]

Ligand

BDBM55085

Substrate/Competitor

n/a

Meas. Tech.

Modulation of the Metabotropic Glutamate Receptor mGluR4: Rat PAM Potency

EC50

6890±n/a nM

Citation

PubChem, PC Modulation of the Metabotropic Glutamate Receptor mGluR4: Rat PAM Potency PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Metabotropic glutamate receptor 4 [Q124R]

Name:

Metabotropic glutamate receptor 4 [Q124R]

Synonyms:

GRM4_RAT | Gprc1d | Grm4 | Mglur4 | glutamate receptor, metabotropic 4 precursor

Type:

Enzyme Catalytic Domain

Mol. Mass.:

101878.86

Organism:

Rattus norvegicus

Description:

gi_12083595

Residue:

912

Sequence:

MSGKGGWAWWWARLPLCLLLSLYAPWVPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGR
GSEGKACGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSL
TFVRALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYA
STAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTLASEGSYGESGVEAFIQ
KSRENGGVCIAQSVKIPREPKTGEFDKIIKRLLETSNARGIIIFANEDDIRRVLEAARRA
NQTGHFFWMGSDSWGSKSAPVLRLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNI
WFAEFWEDNFHCKLSRHALKKGSHIKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHAL
HAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQY
QLRNGSAEYKVIGSWTDHLHLRIERMQWPGSGQQLPRSICSLPCQPGERKKTVKGMACCW
HCEPCTGYQYQVDRYTCKTCPYDMRPTENRTSCQPIPIVKLEWDSPWAVLPLFLAVVGIA
ATLFVVVTFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLG
LGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFILISLQLLGICVWFVV
DPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPET
FNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMP
KVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLETPALAT
KQTYVTYTNHAI

BDBM55085

n/a

Name

BDBM55085

Synonyms:

N-(3-chloro-4-succinimido-phenyl)picolinamide | N-[3-chloro-4-(2,5-dioxo-1-pyrrolidinyl)phenyl]-2-pyridinecarboxamide | N-[3-chloro-4-(2,5-dioxopyrrolidin-1-yl)phenyl]pyridine-2-carboxamide | N-[4-[2,5-bis(oxidanylidene)pyrrolidin-1-yl]-3-chloranyl-phenyl]pyridine-2-carboxamide | VU0365485-1 | cid_46869943

Type

Small organic molecule

Emp. Form.

C16H12ClN3O3

Mol. Mass.

329.738

SMILES

Oc1ccc(O)n1-c1ccc(NC(=O)c2ccccn2)cc1Cl |(3.08,5.02,;4.54,5.5,;5.02,6.96,;6.56,6.96,;7.04,5.5,;8.5,5.02,;5.79,4.59,;5.79,3.05,;7.12,2.28,;7.12,.74,;5.79,-.03,;5.79,-1.57,;7.12,-2.34,;8.46,-1.57,;7.12,-3.88,;5.79,-4.65,;5.79,-6.19,;7.12,-6.96,;8.46,-6.19,;8.46,-4.65,;4.46,.74,;4.46,2.28,;3.12,3.05,)|

Structure