| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Metabotropic glutamate receptor 4 [Q124R] |
|---|
| Ligand | BDBM55081 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Modulation of the Metabotropic Glutamate Receptor mGluR4: Rat PAM Potency |
|---|
| EC50 | 380±n/a nM |
|---|
| Citation |  PubChem, PC Modulation of the Metabotropic Glutamate Receptor mGluR4: Rat PAM Potency PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Metabotropic glutamate receptor 4 [Q124R] |
|---|
| Name: | Metabotropic glutamate receptor 4 [Q124R] |
|---|
| Synonyms: | GRM4_RAT | Gprc1d | Grm4 | Mglur4 | glutamate receptor, metabotropic 4 precursor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 101878.86 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | gi_12083595 |
|---|
| Residue: | 912 |
|---|
| Sequence: | MSGKGGWAWWWARLPLCLLLSLYAPWVPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGR
GSEGKACGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSL
TFVRALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYA
STAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTLASEGSYGESGVEAFIQ
KSRENGGVCIAQSVKIPREPKTGEFDKIIKRLLETSNARGIIIFANEDDIRRVLEAARRA
NQTGHFFWMGSDSWGSKSAPVLRLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNI
WFAEFWEDNFHCKLSRHALKKGSHIKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHAL
HAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQY
QLRNGSAEYKVIGSWTDHLHLRIERMQWPGSGQQLPRSICSLPCQPGERKKTVKGMACCW
HCEPCTGYQYQVDRYTCKTCPYDMRPTENRTSCQPIPIVKLEWDSPWAVLPLFLAVVGIA
ATLFVVVTFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLG
LGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFILISLQLLGICVWFVV
DPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPET
FNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMP
KVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLETPALAT
KQTYVTYTNHAI
|
|
|
|---|
| BDBM55081 |
|---|
| n/a |
|---|
| Name | BDBM55081 |
|---|
| Synonyms: | ML182 | VU0400195-3 | cid_46869947 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H16ClN3O3 |
|---|
| Mol. Mass. | 393.823 |
|---|
| SMILES | [H][C@@]12C[C@@]([H])(C=C1)[C@]1([H])C2C(=O)N(C1=O)c1ccc(NC(=O)c2ccccn2)cc1Cl |c:5,TLB:10:9:2:5.6,THB:13:7:2:5.6| |
|---|
| Structure | 
|
|---|
Search and Browse
