| Reaction Details |
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 | Report a problem with these data |
| Target | M18 aspartyl aminopeptidase |
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| Ligand | BDBM55098 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP). |
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| IC50 | 350.49±n/a nM |
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| Citation |  PubChem, PC QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP). PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| M18 aspartyl aminopeptidase |
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| Name: | M18 aspartyl aminopeptidase |
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| Synonyms: | n/a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 65642.43 |
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| Organism: | Plasmodium falciparum 3D7 |
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| Description: | gi_23505220 |
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| Residue: | 570 |
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| Sequence: | MDKKAREYAQDALKFIQRSGSNFLACKNLKERLENNGFINLSEGETWNLNKNEGYVLCKE
NRNICGFFVGKNFNIDTGSILISIGHIDSCALKISPNNNVIKKKIHQINVECYGSGLWHT
WFDRSLGLSGQVLYKKGNKLVEKLIQINKSVLFLPSLAIHLQNRTRYDFSVKINYENHIK
PIISTTLFNQLNKCKRNNVHHDTILTTDTKFSHKENSQNKRDDQMCHSFNDKDVSNHNLD
KNTIEHLTNQQNEEKNKHTKDNPNSKDIVEHINTDNSYPLLYLLSKELNCKEEDILDFEL
CLMDTQEPCFTGVYEEFIEGARFDNLLGSFCVFEGFIELVNSIKNHTSNENTNHTNNITN
DINDNIHNNLYISIGYDHEEIGSLSEVGARSYCTKNFIDRIISSVFKKEIHEKNLSVQEI
YGNLVNRSFILNVDMAHCSHPNYPETVQDNHQLFFHEGIAIKYNTNKNYVTSPLHASLIK
RTFELYYNKYKQQIKYQNFMVKNDTPCGSTVGSMVAANLSMPGIDIGIPQLAMHSIREIA
AVHDVFFLIKGVFAFYTYYNQVLSTCVHDK
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| BDBM55098 |
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| n/a |
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| Name | BDBM55098 |
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| Synonyms: | (1,3-dioxoisoindol-2-yl)methyl 2-(1H-1,2,4-triazol-5-ylsulfanyl)acetate | (2H-[1,2,4]Triazol-3-ylsulfanyl)-acetic acid 1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl ester | 2-(1H-1,2,4-triazol-5-ylthio)acetic acid (1,3-dioxo-2-isoindolyl)methyl ester | 2-(1H-1,2,4-triazol-5-ylthio)acetic acid phthalimidomethyl ester | MLS000031579 | SMR000010622 | [1,3-bis(oxidanylidene)isoindol-2-yl]methyl 2-(1H-1,2,4-triazol-5-ylsulfanyl)ethanoate | cid_650854 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H10N4O4S |
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| Mol. Mass. | 318.308 |
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| SMILES | O=C(CSc1nnc[nH]1)OCN1C(=O)c2ccccc2C1=O |
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| Structure | 
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