Reaction Details |
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Target | M18 aspartyl aminopeptidase |
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Ligand | BDBM55142 |
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Substrate/Competitor | n/a |
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Meas. Tech. | QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP). |
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IC50 | 609.09±n/a nM |
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Citation | PubChem, PC QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP). PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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M18 aspartyl aminopeptidase |
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Name: | M18 aspartyl aminopeptidase |
Synonyms: | n/a |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 65642.43 |
Organism: | Plasmodium falciparum 3D7 |
Description: | gi_23505220 |
Residue: | 570 |
Sequence: | MDKKAREYAQDALKFIQRSGSNFLACKNLKERLENNGFINLSEGETWNLNKNEGYVLCKE
NRNICGFFVGKNFNIDTGSILISIGHIDSCALKISPNNNVIKKKIHQINVECYGSGLWHT
WFDRSLGLSGQVLYKKGNKLVEKLIQINKSVLFLPSLAIHLQNRTRYDFSVKINYENHIK
PIISTTLFNQLNKCKRNNVHHDTILTTDTKFSHKENSQNKRDDQMCHSFNDKDVSNHNLD
KNTIEHLTNQQNEEKNKHTKDNPNSKDIVEHINTDNSYPLLYLLSKELNCKEEDILDFEL
CLMDTQEPCFTGVYEEFIEGARFDNLLGSFCVFEGFIELVNSIKNHTSNENTNHTNNITN
DINDNIHNNLYISIGYDHEEIGSLSEVGARSYCTKNFIDRIISSVFKKEIHEKNLSVQEI
YGNLVNRSFILNVDMAHCSHPNYPETVQDNHQLFFHEGIAIKYNTNKNYVTSPLHASLIK
RTFELYYNKYKQQIKYQNFMVKNDTPCGSTVGSMVAANLSMPGIDIGIPQLAMHSIREIA
AVHDVFFLIKGVFAFYTYYNQVLSTCVHDK
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BDBM55142 |
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n/a |
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Name | BDBM55142 |
Synonyms: | 3-nitro-4-(1H-1,2,4-triazol-5-ylthio)benzoic acid [2-(carbethoxyamino)-2-keto-ethyl] ester | 3-nitro-4-(1H-1,2,4-triazol-5-ylthio)benzoic acid [2-(ethoxycarbonylamino)-2-oxoethyl] ester | MLS001004551 | SMR000348099 | [2-(ethoxycarbonylamino)-2-oxidanylidene-ethyl] 3-nitro-4-(1H-1,2,4-triazol-5-ylsulfanyl)benzoate | [2-(ethoxycarbonylamino)-2-oxoethyl] 3-nitro-4-(1H-1,2,4-triazol-5-ylsulfanyl)benzoate | cid_2083851 |
Type | Small organic molecule |
Emp. Form. | C14H13N5O7S |
Mol. Mass. | 395.347 |
SMILES | CCOC(=O)NC(=O)COC(=O)c1ccc(Sc2nnc[nH]2)c(c1)[N+]([O-])=O |
Structure |
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