Reaction Details | |||
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Target | M18 aspartyl aminopeptidase | ||
Ligand | BDBM50088347 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP). | ||
IC50 | 1945±n/a nM | ||
Citation | PubChem, PC QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP). PubChem Bioassay(2009)[AID] | ||
More Info.: | Get all data from this article, Solution Info, Assay Method | ||
M18 aspartyl aminopeptidase | |||
Name: | M18 aspartyl aminopeptidase | ||
Synonyms: | n/a | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 65642.43 | ||
Organism: | Plasmodium falciparum 3D7 | ||
Description: | gi_23505220 | ||
Residue: | 570 | ||
Sequence: |
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BDBM50088347 | |||
n/a | |||
Name | BDBM50088347 | ||
Synonyms: | 1,4-Bis-[3-(3,4-dihydroxy-phenyl)-acryloyloxy]-3,5-dihydroxy-cyclohexanecarboxylic acid | CHEMBL67233 | cid_14446 | ||
Type | Small organic molecule | ||
Emp. Form. | C25H24O12 | ||
Mol. Mass. | 516.4509 | ||
SMILES | OC1CC(CC(O)C1OC(=O)\C=C/c1ccc(O)c(O)c1)(OC(=O)\C=C/c1ccc(O)c(O)c1)C(O)=O |(15.05,-16.52,;15.01,-17.81,;17.21,-17.81,;18.36,-19.35,;17.21,-20.79,;15.01,-20.79,;15.01,-22.3,;13.89,-19.35,;13.89,-20.72,;12.55,-21.55,;11.17,-20.79,;12.55,-23.21,;11.29,-23.94,;10.01,-23.12,;10.01,-21.68,;8.68,-20.98,;7.43,-21.74,;6.08,-21.04,;7.43,-23.21,;6.12,-23.98,;8.73,-23.91,;18.36,-20.91,;19.71,-21.65,;21.08,-20.95,;19.71,-23.22,;20.99,-23.87,;22.27,-22.99,;22.27,-21.34,;23.45,-20.5,;24.9,-21.25,;26.26,-20.6,;24.9,-23.05,;26.28,-23.65,;23.64,-23.68,;18.36,-17.81,;19.77,-16.98,;17.63,-16.39,)| | ||
Structure |