| Reaction Details |
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 | Report a problem with these data |
| Target | M18 aspartyl aminopeptidase |
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| Ligand | BDBM55151 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP). |
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| IC50 | 1486±n/a nM |
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| Citation |  PubChem, PC QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP). PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| M18 aspartyl aminopeptidase |
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| Name: | M18 aspartyl aminopeptidase |
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| Synonyms: | n/a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 65642.43 |
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| Organism: | Plasmodium falciparum 3D7 |
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| Description: | gi_23505220 |
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| Residue: | 570 |
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| Sequence: | MDKKAREYAQDALKFIQRSGSNFLACKNLKERLENNGFINLSEGETWNLNKNEGYVLCKE
NRNICGFFVGKNFNIDTGSILISIGHIDSCALKISPNNNVIKKKIHQINVECYGSGLWHT
WFDRSLGLSGQVLYKKGNKLVEKLIQINKSVLFLPSLAIHLQNRTRYDFSVKINYENHIK
PIISTTLFNQLNKCKRNNVHHDTILTTDTKFSHKENSQNKRDDQMCHSFNDKDVSNHNLD
KNTIEHLTNQQNEEKNKHTKDNPNSKDIVEHINTDNSYPLLYLLSKELNCKEEDILDFEL
CLMDTQEPCFTGVYEEFIEGARFDNLLGSFCVFEGFIELVNSIKNHTSNENTNHTNNITN
DINDNIHNNLYISIGYDHEEIGSLSEVGARSYCTKNFIDRIISSVFKKEIHEKNLSVQEI
YGNLVNRSFILNVDMAHCSHPNYPETVQDNHQLFFHEGIAIKYNTNKNYVTSPLHASLIK
RTFELYYNKYKQQIKYQNFMVKNDTPCGSTVGSMVAANLSMPGIDIGIPQLAMHSIREIA
AVHDVFFLIKGVFAFYTYYNQVLSTCVHDK
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| BDBM55151 |
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| n/a |
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| Name | BDBM55151 |
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| Synonyms: | 1-(3,4-Dihydroxy-phenyl)-2-(4-hydroxy-6-methyl-pyrimidin-2-ylsulfanyl)-ethanone | 2-[2-(3,4-dihydroxyphenyl)-2-oxoethyl]sulfanyl-6-methyl-1H-pyrimidin-4-one | 2-[2-[3,4-bis(oxidanyl)phenyl]-2-oxidanylidene-ethyl]sulfanyl-6-methyl-1H-pyrimidin-4-one | 2-[[2-(3,4-dihydroxyphenyl)-2-keto-ethyl]thio]-6-methyl-1H-pyrimidin-4-one | 2-[[2-(3,4-dihydroxyphenyl)-2-oxoethyl]thio]-6-methyl-1H-pyrimidin-4-one | CHEMBL209453 | MLS001212148 | SMR000518041 | cid_687937 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H12N2O4S |
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| Mol. Mass. | 292.31 |
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| SMILES | Cc1cc(=O)[nH]c(SCC(=O)c2ccc(O)c(O)c2)n1 |
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| Structure | 
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