Ki Summary

Reaction Details

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Target

Streptokinase A

Ligand

BDBM56897

Substrate/Competitor

n/a

Meas. Tech.

Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression

EC50

150000±n/a nM

Citation

PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Streptokinase A

Name:

Streptokinase A

Synonyms:

STRP_STRP1 | ska | streptokinase A precursor

Type:

Enzyme Catalytic Domain

Mol. Mass.:

49924.80

Organism:

Streptococcus pyogenes M1 GAS

Description:

gi_15675770

Residue:

440

Sequence:

MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVF
INFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSN
DGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQ
AKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGY
TIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKY
YVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAK
LLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEER
KAYSYLRDTGTPIPDNPKDK

BDBM56897

n/a

Name

BDBM56897

Synonyms:

MLS000071820 | N-[2-(4-Methoxy-phenyl)-6-methyl-2H-benzotriazol-5-yl]-isobutyramide | N-[2-(4-methoxyphenyl)-6-methyl-5-benzotriazolyl]-2-methylpropanamide | N-[2-(4-methoxyphenyl)-6-methyl-benzotriazol-5-yl]-2-methyl-propanamide | N-[2-(4-methoxyphenyl)-6-methyl-benzotriazol-5-yl]-2-methyl-propionamide | N-[2-(4-methoxyphenyl)-6-methylbenzotriazol-5-yl]-2-methylpropanamide | SMR000011222 | cid_651820

Type

Small organic molecule

Emp. Form.

C18H20N4O2

Mol. Mass.

324.377

SMILES

COc1ccc(cc1)-n1nc2cc(C)c(NC(=O)C(C)C)cc2n1

Structure