Ki Summary

Reaction Details

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Target

Streptokinase A

Ligand

BDBM58084

Substrate/Competitor

n/a

Meas. Tech.

Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression

EC50

150000±n/a nM

Citation

PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Streptokinase A

Name:

Streptokinase A

Synonyms:

STRP_STRP1 | ska | streptokinase A precursor

Type:

Enzyme Catalytic Domain

Mol. Mass.:

49924.80

Organism:

Streptococcus pyogenes M1 GAS

Description:

gi_15675770

Residue:

440

Sequence:

MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVF
INFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSN
DGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQ
AKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGY
TIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKY
YVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAK
LLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEER
KAYSYLRDTGTPIPDNPKDK

BDBM58084

n/a

Name

BDBM58084

Synonyms:

(5E)-1-allyl-5-[1-[4-(dimethylamino)anilino]propylidene]barbituric acid | (5E)-5-[1-[4-(dimethylamino)anilino]propylidene]-1-prop-2-enyl-1,3-diazinane-2,4,6-trione | (5E)-5-[1-[[4-(dimethylamino)phenyl]amino]propylidene]-1-prop-2-enyl-1,3-diazinane-2,4,6-trione | 1-Allyl-5-[1-(4-dimethylamino-phenylamino)-prop-(E)-ylidene]-pyrimidine-2,4,6-trione | MLS000559834 | SMR000438315 | cid_6141365

Type

Small organic molecule

Emp. Form.

C18H22N4O3

Mol. Mass.

342.3923

SMILES

CCC(Nc1ccc(cc1)N(C)C)=C1C(=O)NC(=O)N(CC=C)C1=O |w:2.2|

Structure