| Reaction Details |
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 | Report a problem with these data |
| Target | Streptokinase A |
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| Ligand | BDBM58087 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression |
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| EC50 | 150000±n/a nM |
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| Citation |  PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Streptokinase A |
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| Name: | Streptokinase A |
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| Synonyms: | STRP_STRP1 | ska | streptokinase A precursor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49924.80 |
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| Organism: | Streptococcus pyogenes M1 GAS |
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| Description: | gi_15675770 |
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| Residue: | 440 |
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| Sequence: | MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVF
INFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSN
DGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQ
AKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGY
TIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKY
YVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAK
LLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEER
KAYSYLRDTGTPIPDNPKDK
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| BDBM58087 |
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| n/a |
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| Name | BDBM58087 |
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| Synonyms: | 2-Cyclohexyl-3-(4-methoxy-benzyl)-10-methyl-3H,10H-pyrimido[4,5-b]quinoline-4,5-dione | 2-cyclohexyl-10-methyl-3-p-anisyl-pyrimido[4,5-b]quinoline-4,5-quinone | 2-cyclohexyl-3-[(4-methoxyphenyl)methyl]-10-methyl-pyrimido[4,5-b]quinoline-4,5-dione | 2-cyclohexyl-3-[(4-methoxyphenyl)methyl]-10-methylpyrimido[4,5-b]quinoline-4,5-dione | MLS000763169 | SMR000439510 | cid_2028520 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H27N3O3 |
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| Mol. Mass. | 429.5109 |
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| SMILES | COc1ccc(Cn2c(nc3n(C)c4ccccc4c(=O)c3c2=O)C2CCCCC2)cc1 |
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| Structure | 
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