| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Streptokinase A |
|---|
| Ligand | BDBM50640 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression |
|---|
| EC50 | 6215±n/a nM |
|---|
| Citation |  PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay(2009)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Streptokinase A |
|---|
| Name: | Streptokinase A |
|---|
| Synonyms: | STRP_STRP1 | ska | streptokinase A precursor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 49924.80 |
|---|
| Organism: | Streptococcus pyogenes M1 GAS |
|---|
| Description: | gi_15675770 |
|---|
| Residue: | 440 |
|---|
| Sequence: | MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVF
INFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSN
DGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQ
AKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGY
TIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKY
YVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAK
LLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEER
KAYSYLRDTGTPIPDNPKDK
|
|
|
|---|
| BDBM50640 |
|---|
| n/a |
|---|
| Name | BDBM50640 |
|---|
| Synonyms: | 2-chloranyl-3-(1H-indazol-6-ylamino)naphthalene-1,4-dione | 2-chloro-3-(1H-indazol-6-ylamino)-1,4-naphthoquinone | 2-chloro-3-(1H-indazol-6-ylamino)naphthalene-1,4-dione | MLS000737237 | SMR000528477 | cid_265940 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H10ClN3O2 |
|---|
| Mol. Mass. | 323.733 |
|---|
| SMILES | ClC1=C(Nc2ccc3cn[nH]c3c2)C(=O)c2ccccc2C1=O |c:1| |
|---|
| Structure | 
|
|---|
Search and Browse
