Ki Summary

Reaction Details

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Target

M17 leucyl aminopeptidase

Ligand

BDBM60164

Substrate/Competitor

n/a

Meas. Tech.

Inhibitors of Plasmodium falciparum M17- Family Leucine Aminopeptidase (M17LAP)

IC50

1210±n/a nM

Citation

PubChem, PC Inhibitors of Plasmodium falciparum M17- Family Leucine Aminopeptidase (M17LAP) PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

M17 leucyl aminopeptidase

Name:

M17 leucyl aminopeptidase

Synonyms:

leucine aminopeptidase

Type:

Enzyme Catalytic Domain

Mol. Mass.:

67834.32

Organism:

Plasmodium falciparum 3D7

Description:

gi_124809582

Residue:

605

Sequence:

MYFSSLCKFLPISEKEKIYLNIVKKRFCKSNIYYNNNNNNIINYNKRGLKFYPFCNNLKK
NINFVNINNKKGINFHSINKERKMASEVPQVVSLDPTSIPIEYNTPIHDIKVQVYDIKGG
CNVEEGLTIFLVNNPGKENGPVKISSKVNDKNVSEFLKDENMEKFNVKLGTSKHFYMFND
NKNSVAVGYVGCGSVADLSEADMKRVVLSLVTMLHDNKLSKLTVVFEINVDKNLFRFFLE
TLFYEYMTDERFKSTDKNVNMEYIKHLGVYINNADTYKEEVEKARVYYFGTYYASQLIAA
PSNYCNPVSLSNAAVELAQKLNLEYKILGVKELEELKMGAYLSVGKGSMYPNKFIHLTYK
SKGDVKKKIALVGKGITFDSGGYNLKAAPGSMIDLMKFDMSGCAAVLGCAYCVGTLKPEN
VEIHFLSAVCENMVSKNSYRPGDIITASNGKTIEVGNTDAEGRLTLADALVYAEKLGVDY
IVDIATLTGAMLYSLGTSYAGVFGNNEELINKILNSSKTSNEPVWWLPIINEYRATLNSK
YADINNISSSVKASSIVASLFLKEFVQNTAWAHIDIAGVSWNFKARKPKGFGVRLLTEFV
LNDAL

BDBM60164

n/a

Name

BDBM60164

Synonyms:

2-(3,5-diketo-2-methyl-thiomorpholin-4-yl)-N-p-phenetyl-acetamide | MLS000624246 | N-(4-ethoxyphenyl)-2-(2-methyl-3,5-dioxo-4-thiomorpholinyl)acetamide | N-(4-ethoxyphenyl)-2-(2-methyl-3,5-dioxothiomorpholin-4-yl)acetamide | N-(4-ethoxyphenyl)-2-[2-methyl-3,5-bis(oxidanylidene)thiomorpholin-4-yl]ethanamide | SMR000323558 | cid_4983381

Type

Small organic molecule

Emp. Form.

C15H18N2O4S

Mol. Mass.

322.379

SMILES

CCOc1ccc(NC(=O)CN2C(=O)CSC(C)C2=O)cc1

Structure