Reaction Details |
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Target | Dual specificity protein phosphatase 3 |
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Ligand | BDBM51141 |
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Substrate/Competitor | n/a |
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Meas. Tech. | uHTS absorbance assay for the identification of compounds that inhibit VHR1. |
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IC50 | 3490±n/a nM |
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Citation | PubChem, PC uHTS absorbance assay for the identification of compounds that inhibit VHR1. PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Dual specificity protein phosphatase 3 |
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Name: | Dual specificity protein phosphatase 3 |
Synonyms: | DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR |
Type: | Hydrolase |
Mol. Mass.: | 20480.58 |
Organism: | Homo sapiens (Human) |
Description: | n/a |
Residue: | 185 |
Sequence: | MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
GKLKP
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BDBM51141 |
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n/a |
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Name | BDBM51141 |
Synonyms: | 2-[4-[(Z)-[3-[2-(1H-indol-3-yl)ethyl]-2-(4-methoxyphenyl)imino-4-oxidanylidene-1,3-thiazolidin-5-ylidene]methyl]phenoxy]ethanoic acid | 2-[4-[(Z)-[3-[2-(1H-indol-3-yl)ethyl]-2-(4-methoxyphenyl)imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl]phenoxy]acetic acid | 2-[4-[(Z)-[3-[2-(1H-indol-3-yl)ethyl]-2-(4-methoxyphenyl)imino-4-oxo-5-thiazolidinylidene]methyl]phenoxy]acetic acid | 2-[4-[(Z)-[3-[2-(1H-indol-3-yl)ethyl]-4-keto-2-(4-methoxyphenyl)imino-thiazolidin-5-ylidene]methyl]phenoxy]acetic acid | MLS000704894 | SMR000231644 | [4-({3-[2-(1H-indol-3-yl)ethyl]-2-[(4-methoxyphenyl)imino]-4-oxo-1,3-thiazolidin-5-ylidene}methyl)phenoxy]acetic acid | cid_5995173 |
Type | Small organic molecule |
Emp. Form. | C29H25N3O5S |
Mol. Mass. | 527.591 |
SMILES | COc1ccc(cc1)\N=C1/S\C(=C/c2ccc(OCC(O)=O)cc2)C(=O)N1CCc1c[nH]c2ccccc12 |
Structure |
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