Ki Summary

Reaction Details

Report a problem with these data

Target

Large T antigen

Ligand

BDBM58948

Substrate/Competitor

n/a

Meas. Tech.

Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents

IC50

9480±n/a nM

Citation

PubChem, PC Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Large T antigen

Name:

Large T antigen

Synonyms:

LT | LT-AG | LT_SV40

Type:

Enzyme Catalytic Domain

Mol. Mass.:

81575.54

Organism:

Simian virus 40

Description:

P03070

Residue:

708

Sequence:

MDKVLNREESLQLMDLLGLERSAWGNIPLMRKAYLKKCKEFHPDKGGDEEKMKKMNTLYK
KMEDGVKYAHQPDFGGFWDATEIPTYGTDEWEQWWNAFNEENLFCSEEMPSSDDEATADS
QHSTPPKKKRKVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYS
VTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDP
FSVIEESLPGGLKEHDFNPEEAEETKQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFE
MCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQM
LTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKR
YWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGG
ESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEFSVPKTLQAR
FVKQIDFRAKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWK
ERLDKEFSLSVYQKMKFNVAMGIGVLDWLRNSDDDDEDSQENADKNEDGGEKNMEDSGHE
TGIDSQSQGSFQAPQSSQSVHDHNQPYHICRGFTCFKKPPTPPPEPET

BDBM58948

n/a

Name

BDBM58948

Synonyms:

4-[[4-(2-oxolanylmethylamino)-2-quinazolinyl]amino]phenol;hydrochloride | 4-[[4-(oxolan-2-ylmethylamino)quinazolin-2-yl]amino]phenol;hydrochloride | 4-[[4-(tetrahydrofurfurylamino)quinazolin-2-yl]amino]phenol;hydrochloride | 4-{4-[(Tetrahydro-furan-2-ylmethyl)-amino]-quinazolin-2-ylamino}-phenol | MLS000026780 | SMR000014418 | cid_2953078

Type

Small organic molecule

Emp. Form.

C19H20N4O2

Mol. Mass.

336.3877

SMILES

Oc1ccc(Nc2nc(NCC3CCCO3)c3ccccc3n2)cc1

Structure