| Reaction Details |
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 | Report a problem with these data |
| Target | Large T antigen |
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| Ligand | BDBM60350 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents |
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| IC50 | 5010±n/a nM |
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| Citation |  PubChem, PC Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Large T antigen |
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| Name: | Large T antigen |
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| Synonyms: | LT | LT-AG | LT_SV40 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 81575.54 |
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| Organism: | Simian virus 40 |
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| Description: | P03070 |
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| Residue: | 708 |
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| Sequence: | MDKVLNREESLQLMDLLGLERSAWGNIPLMRKAYLKKCKEFHPDKGGDEEKMKKMNTLYK
KMEDGVKYAHQPDFGGFWDATEIPTYGTDEWEQWWNAFNEENLFCSEEMPSSDDEATADS
QHSTPPKKKRKVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYS
VTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDP
FSVIEESLPGGLKEHDFNPEEAEETKQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFE
MCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQM
LTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKR
YWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGG
ESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEFSVPKTLQAR
FVKQIDFRAKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWK
ERLDKEFSLSVYQKMKFNVAMGIGVLDWLRNSDDDDEDSQENADKNEDGGEKNMEDSGHE
TGIDSQSQGSFQAPQSSQSVHDHNQPYHICRGFTCFKKPPTPPPEPET
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| BDBM60350 |
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| n/a |
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| Name | BDBM60350 |
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| Synonyms: | 3-Methyl-5-[(4-morpholin-4-yl-phenylamino)-methyl]-1-phenyl-1,7-dihydro-pyrazolo[3,4-b]pyridin-6-one | 3-methyl-5-[(4-morpholin-4-ylanilino)methyl]-1-phenyl-2H-pyrazolo[3,4-b]pyridin-6-one | 3-methyl-5-[(4-morpholinoanilino)methyl]-1-phenyl-2H-pyrazolo[3,4-b]pyridin-6-one | 3-methyl-5-[[(4-morpholin-4-ylphenyl)amino]methyl]-1-phenyl-2H-pyrazolo[3,4-b]pyridin-6-one | 3-methyl-5-[[4-(4-morpholinyl)anilino]methyl]-1-phenyl-2H-pyrazolo[3,4-b]pyridin-6-one | MLS000027200 | SMR000000917 | cid_654368 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H25N5O2 |
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| Mol. Mass. | 415.4876 |
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| SMILES | Cc1nn(-c2ccccc2)c2[nH]c(=O)c(CNc3ccc(cc3)N3CCOCC3)cc12 |
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| Structure | 
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