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Targetlarge T antigen
LigandBDBM60363
Substrate/Competitorn/a
Meas. Tech.Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents
IC50 4830±n/a nM
Citation PubChem PC Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents PubChem Bioassay (2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
large T antigen
Name:large T antigen
Synonyms:LT | LT-AG
Type:Enzyme Catalytic Domain
Mol. Mass.:81575.54
Organism:Simian virus 40
Description:P03070
Residue:708
Sequence:
MDKVLNREESLQLMDLLGLERSAWGNIPLMRKAYLKKCKEFHPDKGGDEEKMKKMNTLYK
KMEDGVKYAHQPDFGGFWDATEIPTYGTDEWEQWWNAFNEENLFCSEEMPSSDDEATADS
QHSTPPKKKRKVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYS
VTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDP
FSVIEESLPGGLKEHDFNPEEAEETKQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFE
MCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQM
LTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKR
YWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGG
ESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEFSVPKTLQAR
FVKQIDFRAKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWK
ERLDKEFSLSVYQKMKFNVAMGIGVLDWLRNSDDDDEDSQENADKNEDGGEKNMEDSGHE
TGIDSQSQGSFQAPQSSQSVHDHNQPYHICRGFTCFKKPPTPPPEPET
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BDBM60363
n/a
NameBDBM60363
Synonyms:(4E)-4-[[(5-amino-1-tetrazolyl)amino]methylidene]-2-methoxy-1-cyclohexa-2,5-dienone | (4E)-4-[[(5-aminotetrazol-1-yl)amino]methylene]-2-methoxy-cyclohexa-2,5-dien-1-one | (4E)-4-[[(5-aminotetrazol-1-yl)amino]methylidene]-2-methoxycyclohexa-2,5-dien-1-one | (4E)-4-[[(5-azanyl-1,2,3,4-tetrazol-1-yl)amino]methylidene]-2-methoxy-cyclohexa-2,5-dien-1-one | MLS000081472 | SMR000043300 | cid_5389555
TypeSmall organic molecule
Emp. Form.C9H10N6O2
Mol. Mass.234.2147
SMILESCOc1cc(C=Nn2nnnc2N)ccc1O |w:6.6|
Structure
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